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human renal proximal tubular epithelial cells hk2  (ATCC)


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    ATCC human renal proximal tubular epithelial cells hk2
    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in <t>HK2</t> cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001
    Human Renal Proximal Tubular Epithelial Cells Hk2, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 4580 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+proximal+tubular+cells+hk2/HK-2/pmc12976243-93-0-20
    Average 99 stars, based on 4580 article reviews
    human renal proximal tubular epithelial cells hk2 - by Bioz Stars, 2026-10
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    1) Product Images from "Comprehensive analysis of PANoptosis-related molecular subtypes and prognostic model development of clear cell renal cell carcinoma"

    Article Title: Comprehensive analysis of PANoptosis-related molecular subtypes and prognostic model development of clear cell renal cell carcinoma

    Journal: Discover Oncology

    doi: 10.1007/s12672-026-04561-9

    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001
    Figure Legend Snippet: Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001

    Techniques Used: Knockdown, Migration, Quantitative Proteomics, Expressing, Colony Assay, Transwell Migration Assay, CCK-8 Assay

    Related Articles

    Cell Culture:

    Article Title: Altered expression of calreticulin during the development of fibrosis.
    Article Snippet: Tissue damage following injury leads to inflammation and fibrosis.. To understand the molecular mechanisms and the proteins involved in the fibrotic process, we used the well-established unilateral ureteric obstruction rat model and we analyzed the alterations at early and late time intervals using a classical proteomic approach.. Data analysis demonstrates a correlation between calreticulin up-regulation and progression of fibrosis.

    Article Title: LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model.
    Article Snippet: .. Human proximal tubular cells (HK2) were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA), and cultured in complete DMEM/F12 medium (Hyclone, USA) supplemented with100 μg/ mL streptomycin, 100 U/mL penicillin, and 10% FBS (Gibco) in a humidified incubator (5% CO2 at 37 °C). .. For the H/R model, cells were cultured in serum-free F12 medium for 24 h, replaced with serum- and glucose-free DMEM medium (Solarbio, Beijing, China), and transferred into a hypoxia (1% O2, 5% CO2, and 94% N2) incubator chamber (Stem cell, UK) for additional 2 h. Cells were then transferred into normoxic conditions (21% O2, 5% CO2, and 74% N2) with a fresh complete F12 culture medium supplemented with recombinant human LIGHT (5 μg/mL, PeproTech, USA) for 24 h to allow reoxygenation and stimulation.

    Article Title: LIGHT deficiency attenuates acute kidney disease development in an in vivo experimental renal ischemia and reperfusion injury model
    Article Snippet: .. Human proximal tubular cells (HK2) were purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA), and cultured in complete DMEM/F12 medium (Hyclone, USA) supplemented with100 μg/mL streptomycin, 100 U/mL penicillin, and 10% FBS (Gibco) in a humidified incubator (5% CO 2 at 37 °C). .. For the H/R model, cells were cultured in serum-free F12 medium for 24 h, replaced with serum- and glucose-free DMEM medium (Solarbio, Beijing, China), and transferred into a hypoxia (1% O 2 , 5% CO 2 , and 94% N 2 ) incubator chamber (Stem cell, UK) for additional 2 h. Cells were then transferred into normoxic conditions (21% O 2 , 5% CO 2 , and 74% N 2 ) with a fresh complete F12 culture medium supplemented with recombinant human LIGHT (5 μg/mL, PeproTech, USA) for 24 h to allow reoxygenation and stimulation.



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    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in <t>HK2</t> cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001
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    Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001

    Journal: Discover Oncology

    Article Title: Comprehensive analysis of PANoptosis-related molecular subtypes and prognostic model development of clear cell renal cell carcinoma

    doi: 10.1007/s12672-026-04561-9

    Figure Lengend Snippet: Knockdown of RBCK1 significantly inhibits ccRCC cell proliferation and migration. A Differential expression analysis of RBCK1 between normal and tumor groups. B–D DSS, PFI, and OS survival curves for low- and high-RBCK1 expression subgroups. E Protein expression levels of RBCK1 in normal and tumor groups based on the CPTAC database. F Protein expression levels of RBCK1 in HK2 cells and 786-O cells with quantitative analysis (n = 3). G Protein expression levels of RBCK1 in HK2 cells and 769-P cells with quantitative analysis (n = 3). H, I Colony formation assay and Transwell migration assay in 786-O cells (n = 3). J, K Colony formation assay and Transwell migration assay in 769-P cells (n = 3). L, M CCK-8 assay showing cell viability at different time points in 786-O and 769-P cells (n = 3). Data are presented as mean ± SD; significance: * P < 0.05, ** P < 0.01, *** P < 0.001

    Article Snippet: Human renal proximal tubular epithelial cells HK2, human ccRCC 786-O cells, and human ccRCC 769-P cells were obtained from the American Type Culture Collection (ATCC, USA).

    Techniques: Knockdown, Migration, Quantitative Proteomics, Expressing, Colony Assay, Transwell Migration Assay, CCK-8 Assay